MSPTM 2019 Annual Scientific Conference
13 - 14 March 2019
InterContinental Kuala Lumpur

Abstract

Title

OPISTHORCHIS VIVERRINI INFECTIONS AND ASSOCIATED RISK FACTORS IN TWO PROVINCES OF NORTHEASTERN THAILAND: A DESCRIPTIVE CROSS-SECTIONAL STUDY

Type
Oral Presentation
Theme
Scaling Up Efforts in Tropical Disease and Vector Control through Evidence-Based Research
Topic
Medical Microbiology & Parasitology

Authors

Main Author
Sriwipa Chuangchaiya1
Presenting Author
Sriwipa Chuangchaiya1
Co-Author
Zulkarnain Md Idris2
Nonglak Laoprom3
Tawan Kimyong1
Oba Lasud1

Authors' Institution

Department / Institution / Country
Community Health / Kasetsart University / Thailand (ไทย)1
Department of Parasitology and Medical Entomology / Universiti, Kebangsaan Malaysia Medical Centre / Malaysia2
Chemistry / Kasetsart University / Thailand (ไทย)3
Content
Abstract Content

Opisthorchis viverrini is still a serious health problem in Northeastern and Northern regions of Thailand. The infection is associated with severe biliary diseases, eventually leading to fatal cholangiocarcinoma. Active surveillance is required to determine updated data for further prevention and control planning. Therefore, this study aimed to examine the prevalence and risk factors for O. viverrini infections in two provinces of Northeastern Thailand. A cross-sectional study was conducted between March and June 2017 at Phon Na Kaeo district of Sakon Nakhon Province and That Phanom district of Nakhon Phanom Province, Thailand. Stool samples were collected and examined for the presence of O. viverrini by Kato-Katz smear technique. Socio-demographic variables and risk factors were collected by a standardised questionnaire. The overall prevalence of O. viverrini among 495 study participants was 15.4% (95% confidence interval [CI] 12.3 – 18.8). The parasite rate was higher in Nakhon Phanom than in Sakon Nakhon (P = 0.009) and differed significantly in adults <45 years old in both provinces (P <0.05). Multivariate regression analyses revealed being labourer (adjusted odd ratio [aOR] 4.7 [95% CI 1.08, 20.38], P = 0.039) and farmer (aOR 5.79 [95% CI 1.45, 31.91], P = 0.015) were positively associated with a higher risk of O. viverrini infection. The present study provides evidence that the surveyed areas of Sakon Nakon Province and Nakhon Phanom Province in Thailand are endemic for O. viverrini infection. Therefore, integrated prevention and control programs continue to be urgently required.

Keywords: Opisthorchis viverrini; Sakon Nakhon; Nakhon Phanom; Risk factors
Requires Audio or Video system for Presentation?: No