MSPTM 2019 Annual Scientific Conference
13 - 14 March 2019
InterContinental Kuala Lumpur

Abstract

Title

LEPTOSPIROSIS: AN INSIGHT INTO COMMUNITY STRUCTURE OF SMALL MAMMALS HOST IN URBAN ENVIRONMENT

Type
Oral Presentation
Theme
Scaling Up Efforts in Tropical Disease and Vector Control through Evidence-Based Research
Topic
Medical Microbiology & Parasitology

Authors

Main Author
Farah Shafawati Mohd-Taib1
Presenting Author
Farah Shafawati Mohd-Taib1
Co-Author
Siti Nabilah Ishak1
Muhammad Afif Yusof
Nurul Natasya Azhari
Asmalia Md Lasim1
Shukor Md-Nor1
Shahrul Anuar Mohd Sah
Vasantha Kumari Neela

Authors' Institution

Department / Institution / Country
Center for Ecosystem and Natural Resource Management, / Faculty of Science and Technology, Universiti Kebangsaan Malaysia / Malaysia1
Content
Abstract Content
Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira and most often acquired through contact with environments contaminated with leptospires shed in the urine of infected mammalian hosts. In urban environment, rodents are well-known as the main carriers of this bacteria, however, there were no intensive study on the community structure of these animals, and how it associated with this bacteria.  Hence, we use a case study from an outbreak in a residential area in Kajang, Selangor, to investigate how community structure of small mammals hosts, associated with the prevalence of Leptospira. One hundred cage traps were placed randomly in and around the houses in five phases with two months interval for a year. Community structure (species, sex, and age) were assigned for each individuals, prior to screening for pathogenic Leptospira, using a partial lipL32 gene from the kidney samples. Throughout the sampling, 185 small mammals have been captured, and were identified into four different species, namely Rattus norvegicus (74.5%, n=138), R. rattus (20%, n=37), Tupaia glis (5%, n=9), and Suncus murinus (0.5%, n=1). From this number, 29 individuals were found PCR positive for pathogenic Leptospira (R. norvegicus, n=20; R. rattus, n=6; T. glis, n=2; S. murinus, n=2). The study shows that Leptospira occurrence in the small mammals was significantly correlated to age category and sampling phases, with Spearman Correlation (rs) p=0.02  and p=0.00 respectively. Adult individuals were highly prevalent with Leptospira infection, whereby February and June were found to associate with high Leptospira prevalent among the small mammals. This information is important in designing a specific control method for rodents in Leptospira outbreak areas. In addition, the intensive sampling and sequential cleaning effort were found to significantly reduce the number of small mammals population, thus should be implemented in intervention strategies in the urban environment.  
Keywords: Leptospira; rodents; urban; community structure; intervention
Requires Audio or Video system for Presentation?: No