MSPTM 2019 Annual Scientific Conference
13 - 14 March 2019
InterContinental Kuala Lumpur

Abstract

Title

PREVALENCE OF STRONGYLOIDES INFECTION IN DIABETIC PATIENTS IN BABOL NORTH OF IRAN

Type
Oral Presentation
Theme
Scaling Up Efforts in Tropical Disease and Vector Control through Evidence-Based Research
Topic
Medical Microbiology & Parasitology

Authors

Main Author
Narges Kalantari1
Presenting Author
Narges Kalantari1
Co-Author
Zeinab Darbandi 2
Salman Ghaffari3
Mohamad Ali Bayani4
Mitra Sharbatkhori5
Masomeh Bayani6

Authors' Institution

Department / Institution / Country
Cellular and Molecular Biology Research Center, / Health Research Institute, Babol University of Medical Sciences / Iran, Islamic Rep. of1
Student Research Committee / Babol University of Medical Sciences / Iran, Islamic Rep. of2
Mycology and Parasitology / Babol University of Medical Sciences / Iran, Islamic Rep. of3
Internal Medicine / Babol University of Medical Sciences / Iran, Islamic Rep. of4
Department of Laboratory Sciences / Babol University of Medical Sciences / Iran, Islamic Rep. of5
Infectious Diseases and Tropical Medicine Research Center / Babol University of Medical Sciences / Iran, Islamic Rep. of6
Content
Abstract Content

Introduction: Strongyloidiasis is caused by a soil transmitted helminth, Strongyloides stercoralis which may be fatal in immunosuppressed patients. The present study aimed to evaluate the prevalence of strongyloidiasis in diabetic patients, in Babol, Northern Iran, using stool examination and enzyme-linked immunosorbent assay (ELISA).

Methods: A single fresh stool and serum sample were taken from each diabetic patient. The stool samples were tested by direct smear and formalin-ether concentration methods. The existence of Strongyloides antibodies in the serum samples were examined by a commercial diagnostic kit (Strongyloides-ELISA).

Results: The overall prevalence rate of Strongyloides infection in the studied patients obtained by coprological methods was 13.3%. The seroprevalence of this infection in diabetic patients was 25.6%. The sensitivity and specificity of ELISA in comparison with coprological methods was 100% and 84.6%, respectively. The seroprevalence rate of this infection was higher in females than males (27.3% vs.19.5%), and among participants living in rural regions compared with urban areas (31% vs. 20%). Nevertheless, these differences were not statistically significant.

Conclusions: The findings obtained from the current study showed that the prevalence of Strongyloides infection in diabetic patients in our region was high. It also showed that the ELISA technique can be used for the diagnosis of individual cases and may use as a screening test to rule out strongyloidiasis in diabetic patients.

Keywords: Diabetes; ELISA; Iran; Strongyloides stercoralis
Requires Audio or Video system for Presentation?: Yes