Abstract

Title

THE PROGNOSTIC VALUE OF ELECTROCARDIOGRAPHIC CHANGES WITH TREATMENT OF PULMONARY EMBOLISM

Type
Free Paper Session 4
Theme
ACC Asia & SCS 32nd Annual Scientific Meeting
Topic
Non-Invasive Cardiac Imaging, Echocardiography, Nuclear Cardiology / Adult Congenital Heart Disease / Cardiac Surgery

Authors

Main Author
Mayank Dalakoti1
Presenting Author
Mayank Dalakoti1
Co-Author
Ching Hui Sia1
Pipin Kojodjojo1

Authors' Institution

Department / Institution / Country
Cardiology / NUHS / Singapore1
Content
Objective(s)

Electrocardiographic (ECG) changes in pulmonary embolism (PE) reflect right heart strain (RHS) and resolution may predict short-term outcomes. This study investigated ECG changes in patients with European Society of Cardiology intermediate-high and high risk PE, and evaluated if persistence of ECG changes after treatment predicted survival to hospital discharge.

Material and Method

Consecutive patients with intermediate-high risk and high risk PE, confirmed by CT pulmonary angiography, were recruited from an academic medical centre registry. 4 ECG parameters indicative of RHS at the time of diagnosis and after treatment of PE, which included thrombolysis and thrombectomy, were reviewed.  Primary outcome was survival to hospital discharge.

Result(s)

The prevalence of ECG abnormalities in 71 patients is shown in the Table. The average age was 62.3 years ± 13.8, and 70.0% of the cohort was female. Following treatment, sinus tachycardia and S1Q3T3 persisted in 47% and 57% respectively (p<0.01). Persistence of ECG changes, however, did not predict survival to hospital discharge. 

Table. Results of changes of electrocardiographic parameters at diagnosis of pulmonary embolism and after treatment (n=71)

ECG Parameters

At time of diagnosis

After treatment

p-value

S1Q3T3

37 (52)

21 (31)

<0.01

Sinus Tachycardia

45 (63)

21 (31)

<0.01

Right Bundle Branch Block

11 (16)

6 (9)

0.10

T wave inversions in V2-V4

31 (44)

38 (56)

0.06

Proportions displayed as number (percentage %)

Conclusion

In patients with intermediate and high-risk PE, resolution of ECG changes with treatment did not predict survival to hospital discharge. 

Keywords: ECG Pulmonary embolism
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