Title Isolation of Immunomodulatory Probiotic Strain to be used in Kimchi |
Type Poster Presentation |
Theme Probiotics and Prebiotics: Excellence in Science and Clinical Translation |
Topic Development of Probiotic and Prebiotic Foods, Medical Foods, Supplements and Drugs |
Main Author Da Min Park1 |
Presenting Author Da Min Park1 |
Co-Author Nam Soo Han1 |
Department / Institution / Country Division of Animal, Horticultural, and Food Sciences / Chungbuk National University / Korea, Rep. (대한민국)1 |
Background and Rationale The demand for probiotics is increasing due to beneficial health effects of probiotics. As in the case of the yogurt products, it is necessary to develop a new probiotic used for the fermentation of Kimchi products. |
Objectives: Indicates the purpose of the study The purpose of this study was to isolate industrially useful and safe probiotic candidates for Kimchi. |
Methodology: Describe pertinent experimental procedures Using various lactic acid bacteria (LAB) isolated from Kimchi and human feces, their survival rates in the gastrointestinal tract were measured by reacting in the simulated conditions and their adhesion capacities on the human colon cells were tested. For the selected strains, TNF-α, IL-6, and IL-12 inducing activities were measured using mouse peritoneal macrophages to test an immmunomodulatory activity. |
Results: Summarize the results of the research Among various LAB tested in acid and bile salt resistance, 11 strains were isolated and they were Lactobacillus spp. (9), and Leuconostoc spp. (2). When cytokine inducing activities were tested, L. mesenteroides EFEL 15 showed the highest values in the secretion of TNF-α, IL-6, and IL-12. |
Conclusions: State the main conclusions L. mesenteroides EFEL 15 can be used as an immunomodulating LAB strain for Kimchi product. |