Health literacy (HL) is a public health concern that refers to an individual's, competence to access, understand, appraise and apply health information to prevent illness and promote a healthy lifestyle. This study aimed to adapt a globally recognized tool for assessing the European Health Literacy Questionnaire (HLS-EU-Q47) into Arabic. The questionnaire was translated into Arabic. The Forward-backward translation method was used for linguistic validity. The content of the questionnaire was judged by public health expert panels. Face validity was assessed among a purposive sample of Libyan parents of primary school students in the West area of Libya. HLS-EUQ47 was administered to 470 Libyan parents of primary school students in the West area of Libya. Construct validity was assessed by confirmatory factor analysis. Convergent validity was examined using the Composite Reliability (CR) and Average Variance Extracted (AVE).  Discriminant validity was tested by examining the square root of AVE for each construct against correlations, reliability was examined using Cronbach's alpha coefficient and Intra-Class Correlation Coefficient. The questionnaire was shown to have good construct validity, satisfactory goodness-of-fit of the data to the hypothetical model in three health literacy domains, high internal consistency (Cronbach's alpha >0.90), satisfactory convergent validity. This study revealed that the HLS-EU-Q47-Arabic was a valid and reliable measuring instrument, satisfactory and comprehensive measuring health literacy survey tool for use in Arab countries.