Abstract

Title

Isolation of Immunomodulatory Probiotic Strain to be used in Kimchi

Type
Poster Presentation
Theme
Probiotics and Prebiotics: Excellence in Science and Clinical Translation
Topic
Development of Probiotic and Prebiotic Foods, Medical Foods, Supplements and Drugs

Authors

Main Author
Da Min Park1
Presenting Author
Da Min Park1
Co-Author
Nam Soo Han1

Authors' Institution

Department / Institution / Country
Division of Animal, Horticultural, and Food Sciences / Chungbuk National University / Korea, Rep. (대한민국)1
Content
Background and Rationale
The demand for probiotics is increasing due to beneficial health effects of probiotics. As in the case of the yogurt products, it is necessary to develop a new probiotic used for the fermentation of Kimchi products.
Objectives: Indicates the purpose of the study
The purpose of this study was to isolate industrially useful and safe probiotic candidates for Kimchi.
Methodology: Describe pertinent experimental procedures
Using various lactic acid bacteria (LAB) isolated from Kimchi and human feces, their survival rates in the gastrointestinal tract were measured by reacting in the simulated conditions and their adhesion capacities on the human colon cells were tested. For the selected strains, TNF-α, IL-6, and IL-12 inducing activities were measured using mouse peritoneal macrophages to test an immmunomodulatory activity.
Results: Summarize the results of the research
Among various LAB tested in acid and bile salt resistance, 11 strains were isolated and they were Lactobacillus spp. (9), and Leuconostoc spp. (2). When cytokine inducing activities were tested, L. mesenteroides EFEL 15 showed the highest values in the secretion of TNF-α, IL-6, and IL-12.
Conclusions: State the main conclusions
L. mesenteroides EFEL 15 can be used as an immunomodulating LAB strain for Kimchi product.
Keywords: Lactic acid bacteria(LAB), Probiotics, Kimchi, Immunomodulatory, L. mesenteroides
Requires Audio or Video system for Presentation?: No